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  • Biomarker can predict aggressive prostate cancer

    When a man is diagnosed with prostate cancer, a host of tools can be used to determine the type and extent of his disease. These tools include a basic PSA blood test, digital rectal exam, tissue biopsy, and a Gleason Score – a mathematical score based on tissue analysis that predicts whether the cancer is aggressive or not and... read more

  • Prostate Brachytherapy Has Good Long-term Outcomes

    Stone and Stock reported a large cohort study, published in the Journal of Urology, of more than 1700 men treated for prostate cancer between 1990 and 2007, with a 10-year mean follow-up. The study included a mixture of patients and treatments: Some men received brachytherapy with iodine alone, and some received brachytherapy with palladium, with or without hormone therapy,... read more

  • Study Supports IL16 Role in Prostate Cancer in African-Americans

    In African-Americans, IL16 polymorphisms appear to play a role in prostate cancer susceptibility, according to research published online Aug 24 in Cancer Epidemiology, Biomarkers & Prevention. Interleukin 16 (IL-16), small cell-signaling protein molecules that are released by a variety of cells (including lymphocytes and some epithelial cells) that has been characterized as a chemoattractant for certain immune cells expressing the... read more

  • Improved Survival for Prostate Cancer Seen in Post-PSA Era

    Overall survival for metastatic prostate cancer is significantly improved in a post-prostate-specific antigen (PSA) era trial compared with two trials conducted before the PSA era. Prostate-specific antigen, or PSA, is a protein produced by cells of the prostate gland. The PSA test measures the level of PSA in a man’s blood. For this test, a blood sample is sent to... read more

  • Caring for Your Bones When You Have Prostate Cancer

    Many men experience bone loss and joint pain related to their prostate cancer. Communicating with your health care team is important to maintaining healthy bones. There are also lifestyle changes you can make to help keep your bones strong. This fact sheet answers some commonly-asked questions about prostate cancer and bone health. It also discusses steps you can take... read more

  • Long-Term Outcomes in Younger Men Following Permanent Prostate Brachytherapy

    Edan Y. Shapiro, Soroush Rais-Bahrami, Carol Morgenstern, Barbara Napolitano, Lee Richstone, Louis Potters Purpose We reviewed the long-term outcomes in men undergoing permanent prostate brachytherapy with a focus on those presenting before age 60 years. Materials and Methods Between 1992 and 2005 a total of 2,119 patients with clinical stage T1–T2, N0, M0 prostate cancer treated with permanent prostate brachytherapy were included in... read more

  • Prostate Cancer detection rates increased by 23%

    TRANSPERINEAL TEMPLATE-GUIDED SATURATION PROSTATE BIOPSIES High-risk prostate cancer represents a therapeutic challenge for both the urologist and radiation oncologist. Patients with prostate cancer used to be diagnosed prior to the PSA era frequently on transurethral resection of the prostate gland. When prostate specific antigen (PSA) came into use for screening prostate cancer patients in the late 1980s, we began seeing... read more

  • Interstitial Brachytherapy Should Be Standard of Care for Treatment of High-Risk Prostate Cancer

    Nathan Bittner, MD, MS University of Washington Seattle, Washington Gregory S. Merrick, MD Wheeling Jesuit University Wheeling, West Virginia Kent E. Wallner, MD Puget Sound Healthcare System Seattle, Washington Wayne M. Butler, PhD Wheeling Jesuit University Wheeling, West Virginia High-risk prostate cancer represents a therapeutic challenge for both the urologist and radiation oncologist. Biochemical outcomes with radical prostatectomy and external-beam radiation therapy are poor in this subset of patients. These unfavorable... read more